List of publications

Published papers and congress abstracts on CMC 001

Articles published in peer-reviewed scientific journals

1. Thomsen HS et al. Increased Manganese Concentration in the Liver After Oral Intake. Acad Radiol 2004; 11: 38-44.
2. Thomsen HS et al. Oral Manganese for Liver Imaging at Three Different Field Strengths. Acad Radiol 2004: 11: 630-636
3. Chabanova E et al. Effects of new manganese agent on tissue intensities in human volunteers: comparison of 0.23, 0.6 and 1.5 T MRI, a part of a phase I trial. Magma 2004; 17: 28-35.
4. Thomsen HS et al. Oral manganese for liver and bile imaging. Acad Radiol 2005; 12 (suppl 1): S21-S23.
5. Chabanova E et al. Imaging Liver Metastases with a New Oral Manganese-Based Contrast Agent. Acad Radiol 2006; 13: 827-832.
6. Barentsz J et al. Commonly used Imaging Techniques for Diagnosis and Staging. J Clin Oncol 2006; 24: 3234–3244
7. Thomsen HS et al. Initial clinical experience with oral manganese (CMC-001) for liver MR imaging. Eur Radiol 2007, 17: 273-278.
8. Møller JM et al. Magnetic Resonance Imaging with Liver-Specific Contrast Agent in Primary Amyloidosis and Intrahepatic Cholestasis. Acta Radiol 2007; 48: 145-149.
9. Rief M et al. Manganese-based oral contrast agent for liver magnetic resonance imaging: evaluation of the time course and dose response of liver signal intensity enhancement. Invest Radiol. 2010; 45: 565-71.
10. Chabanova E et al. Manganese based MR Contrast Agents: Formulation and Clinical Applications. Open Drug Safety Journal 2011; 2: 29-38.

Abstracts Presented at Scientific Congresses

1. Thomsen HS et al. A new combined oral liver and bowel agent is not taken up by the kidneys. Society of Uroradiology, Cancun 2003.
2. Thomsen HS et al. Oral manganese for liver imaging at three different field strengths. Contrast Media Research Meeting, CMR 03, San Diego 2003.
3. H. Dekker et al. Oral manganese as contrast medium in detecting liver metastases with MRI at 1.5 and 3T – early experience. Annual congress of Society of Computerised Tomography and Magnetic Resonance Imaging, Florida, March 2005.
4. Thomsen HS et al. Oral manganese for Liver Imaging: Uptake of manganese in the kidneys. Society of Uroradiology - San Antonio 2005.
5. Chabanova E et al. Imaging Liver Metastases with new Oral Manganese Contrast. Abstract. European Society of Magnetic Resonance in Medicine and Biology Congress. Clinical Focus Session no 27, Vienna, September 2005.
6. Thomsen HS et al. Preliminary clinical experience with oral manganese (CMC-001) for liver imaging in daily routine. Contrast Media Research Meeting, CMR 05, Evian 2005.
7. Dekker H et al. Oral Manganese as Contrast Medium in Detecting Liver Metastases with MR Imaging at 1.5 and 3 T. Abstract SSM 12-03. RSNA Annual Meeting, Chicago, December 2005.
8. Dekker H et al. Oral Manganese as Contrast Medium in Detecting Liver Metastases with MR Imaging at 1.5 and 3 T. Abstract B-456. European Congress of Radiology, Vienna, March 2006.
9. S. Takahashi et al. Oral Manganese Enhanced MRI: Possible tool for non-invasive visualization for regional portal flow in the liver. Abstract E-114. ESGAR/SGR Congress, Crete, Greece; June 19-23, 2006.
10. Brismar TB et al. The Sensitivity and Specificity of CMC 001 (An Oral MR Contrast Agent) in Detecting Colon Cancer Metastases in Liver: A Phase 3 Trial. Abstract SST03-09. RSNA Annual Meeting, Chicago, November 2007.
11. Albiin N et al. Liver magnetic resonance imaging of colorectal cancer metastases: Using the novel perorale contrast agent CMC. Abstract 32. Progress in Radiology 2008, Tokyo, September 26-28, 2008.
12. Reif M et al. Oral manganese-based contrast agent CMC-001 for liver MR imaging in patients with Hepatic metastases: initial experience of a phase II trial. Contrast Media Research Meeting, CMR 09, Copenhagen, 11-13 October, 2009.
13. Møller J. Adverse reactions/Discomfort to CMC-001. Contrast Media Research, CMR 09, Copenhagen, 11-13 October, 2009.
14. Brismar T et al. A New Oral Contrast Media to Detect Liver Metastases: Results from a Phase 3 Study. Abstract SSGo8-2 RSNA Annual Meeting, Chicago, November 29 – December 4, 2009.
15. Dekker H et al. Oral Manganese as Contrast Medium for MR Imaging Detection of Liver Metastases: A Phase II Clinical Study. Abstract SSG08-03. RSNA Annual Meeting, Chicago, November 29 – December 4, 2009.
16. Rief M et al. Diagnostic time window for liver MRI after administration of an oral manganese-based contrast agent (CMC-001). Abstract B-768. European Congress of Radiology, Vienna, 4-8 March, 2010.